Transglutaminase 2 anticorps

N° du produit ABIN2463067

Détail du produit anti-Transglutaminase 2 anticorps

Antigène: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transglutaminase 2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TGM2.

Information d'application

Indications d'application: TGM2 antibody can be used for detection of TGM2 by ELISA at 1:312500. TGM2 antibody can be used for detection of TGM2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TGM2 antibody at -20 °C.

Détails sur Transglutaminase 2

Antigène: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Autre désignation: TGM2 (TGM2 Produits)

Synonymes: anticorps G-ALPHA-h, anticorps GNAH, anticorps TG2, anticorps TGC, anticorps tgm2, anticorps zgc:101081, anticorps TgaseII, anticorps TGM2, anticorps fc12b04, anticorps wu:fc12b04, anticorps zgc:136700, anticorps TGL2, anticorps G[a]h, anticorps TGase2, anticorps tTG, anticorps tTGas, anticorps transglutaminase 2, anticorps transglutaminase 2, C polypeptide A, anticorps transglutaminase 2b, anticorps transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), anticorps transglutaminase 2, C polypeptide, anticorps TGM2, anticorps tgm2a, anticorps Tgm2, anticorps tgm2b

Sujet: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, TGM2 is the autoantigen implicated in celiac disease.Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 62 kDa

ID gène: 7052

NCBI Accession: NP_945189

Pathways: Tube Formation, Thromboxane A2 Receptor Signaling