GADD45B anticorps

N° du produit ABIN2463174

Détail du produit anti-GADD45B anticorps

Antigène: GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GADD45B est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GADD45B.

Information d'application

Indications d'application: GADD45B antibody can be used for detection of GADD45B by ELISA at 1:1562500. GADD45B antibody can be used for detection of GADD45B by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GADD45B antibody at -20 °C.

Détails sur GADD45B

Antigène: GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))

Autre désignation: GADD45B (GADD45B Produits)

Synonymes: anticorps GADD45BETA, anticorps MYD118, anticorps AI323528, anticorps Myd118, anticorps CS131, anticorps cb196, anticorps gadd45b, anticorps gadd45b2, anticorps sb:cb196, anticorps zgc:73104, anticorps gadd45beta, anticorps wu:fa92d10, anticorps wu:fa98h12, anticorps wu:fk65h03, anticorps zgc:111973, anticorps gadd45b1, anticorps gadd45bl, anticorps zgc:112453, anticorps growth arrest and DNA damage inducible beta, anticorps growth arrest and DNA-damage-inducible 45 beta, anticorps growth arrest and DNA-damage-inducible, beta, anticorps growth arrest and DNA-damage-inducible, beta a, anticorps growth arrest and DNA-damage-inducible, beta b, anticorps GADD45B, anticorps Gadd45b, anticorps gadd45ba, anticorps gadd45bb

Sujet: The function of GADD45B is involved in the regulation of growth and apoptosis.This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 18 kDa

ID gène: 4616

NCBI Accession: NP_056490

UniProt: O75293

Pathways: Cycle Cellulaire