DOK1 anticorps
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- Antigène Voir toutes DOK1 Anticorps
- DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DOK1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DOK1.
- Top Product
- Discover our top product DOK1 Anticorps primaire
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- Indications d'application
- DOK1 antibody can be used for detection of DOK1 by ELISA at 1:62500. DOK1 antibody can be used for detection of DOK1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store DOK1 antibody at -20 °C.
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- Antigène
- DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
- Autre désignation
- DOK1 (DOK1 Produits)
- Synonymes
- anticorps P62DOK, anticorps Dok-1, anticorps AW557123, anticorps p62DOK, anticorps dok1, anticorps zgc:76914, anticorps docking protein 1, anticorps docking protein 1b, anticorps DOK1, anticorps Dok1, anticorps dok1b
- Sujet
- DOK1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
- Poids moléculaire
- 53 kDa
- ID gène
- 1796
- NCBI Accession
- NP_001372
- UniProt
- Q99704
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