NAPA anticorps

N° du produit ABIN2463756

Détail du produit anti-NAPA anticorps

Antigène: NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAPA est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by Protein A/G affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NAPA.

Information d'application

Indications d'application: NAPA antibody can be used for detection of NAPA by ELISA at 1:75000. NAPA antibody can be used for detection of NAPA by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NAPA antibody at -20 °C.

Détails sur NAPA

Antigène: NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))

Autre désignation: NAPA (NAPA Produits)

Synonymes: anticorps SNAPA, anticorps wu:fa26c04, anticorps zgc:63906, anticorps napb, anticorps 1500039N14Rik, anticorps AW209189, anticorps RA81, anticorps SNARE, anticorps a-SNAP, anticorps hyh, anticorps alpha-SNAP, anticorps Alpha-SNAP, anticorps NSF attachment protein alpha, anticorps N-ethylmaleimide-sensitive factor attachment protein, alpha b, anticorps NSF attachment protein alpha L homeolog, anticorps N-ethylmaleimide-sensitive factor attachment protein, alpha, anticorps N-ethylmaleimide sensitive fusion protein attachment protein alpha, anticorps soluble NSF attachment protein, anticorps NAPA, anticorps napab, anticorps napa.L, anticorps napa, anticorps EHI_000300, anticorps Napa, anticorps LOC102577508

Sujet: The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37 % , 60 %, and 67 % identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively.

Poids moléculaire: 33 kDa

ID gène: 8775

NCBI Accession: NP_003818

UniProt: P54920

Pathways: Synaptic Vesicle Exocytosis, Asymmetric Protein Localization