MITF anticorps (AA 287-417)

N° du produit ABIN2467990

Détail du produit anti-MITF anticorps

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Épitope: AA 287-417

Reactivité: Humain

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp MITF est non-conjugé

Application: Western Blotting (WB)

Purification: Immunoaffinity Purified

Information d'application

Indications d'application: Microphthalmia-associated transcription factor antibody can be used for the detection of Microphthalmia-associated transcription factor by Western Blot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Agent conservateur: Without preservative

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Stockage commentaire: MITF antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Détails sur MITF

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Autre désignation: MITF (MITF Produits)

Synonymes: anticorps MITF, anticorps ws2a, anticorps mitfa, anticorps MITF-A, anticorps LOC100313655, anticorps mitfb, anticorps CMM8, anticorps MI, anticorps WS2, anticorps WS2A, anticorps bHLHe32, anticorps BCC2, anticorps Bhlhe32, anticorps Gsfbcc2, anticorps Vitiligo, anticorps Wh, anticorps bw, anticorps mi, anticorps vit, anticorps MITF-H, anticorps MITF-M, anticorps CMI9, anticorps melanogenesis associated transcription factor, anticorps microphthalmia-associated transcription factor, anticorps microphthalmia-associated transcription factor S homeolog, anticorps Microphthalmia, anticorps MITF, anticorps mitf, anticorps LOC100313655, anticorps mitf.S, anticorps LOC100534525, anticorps MICROP, anticorps Mitf

Sujet: FUNCTION: Transcription factor for tyrosinase and tyrosinase-related protein 1. Binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') found in the tyrosinase promoter. Plays a critical role in the differentiation of various cell types as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

DISEASE: Defects in MITF are the cause of Tietz syndrome [MIM:103500]. It is an autosomal dominant disorder characterized by generalized hypopigmentation and profound, congenital, bilateral deafness. Penetrance is complete

Poids moléculaire: 58.8 kDa (calculated)

ID gène: 4286

NCBI Accession: NP_000239

UniProt: O75030

Pathways: Chromatin Binding