AKT3 anticorps (AA 119-136)

N° du produit ABIN2469638

Détail du produit anti-AKT3 anticorps

Antigène: AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))

Épitope: AA 119-136

Reactivité: Humain, Souris, Rat, Singe, Chien, Poulet, Boeuf (Vache), Porc, Roussette (Chauve-souris), Cheval, Lapin, Gibbon, Gorilla

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AKT3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Protein G Column

Immunogène: AKT3 monoclonal antibody was raised against amino acids 119 - 136 of AKT3 (Human).

Clone: 66C1247-1

Isotype: IgG1

Information d'application

Indications d'application: AKT3 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200, immunofluorescence starting at 1:200 - 1:1000, and flow cytometry starting at 1:200 - 1:400.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 0.05 % BSA, 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store AKT3 antibody at 4 °C or -20 °C.

Détails sur AKT3

Antigène: AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))

Autre désignation: AKT3 (AKT3 Produits)

Synonymes: anticorps MPPH, anticorps PKB-GAMMA, anticorps PKBG, anticorps PRKBG, anticorps RAC-PK-gamma, anticorps RAC-gamma, anticorps STK-2, anticorps AI851531, anticorps D930002M15Rik, anticorps Nmf350, anticorps Pkbg, anticorps AKT serine/threonine kinase 3, anticorps thymoma viral proto-oncogene 3, anticorps v-akt murine thymoma viral oncogene homolog 3b, anticorps AKT3, anticorps Akt3, anticorps akt3b

Sujet: Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activat phosphtidylinositol 3-kinase (PI 3-kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI-3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). Akt1, 2 and 3 contain a key regulatory serine phosphorylation site in the carboxy-terminal region of the protein. Akt/PKB phosphorylation is critical for it activity.

ID gène: 10000

UniProt: Q9Y243

Pathways: Signalisation PI3K-Akt, Signalisation RTK, Signalisation TLR, Hepatitis C, VEGF Signaling