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CTLA4 anticorps (PE)
CTLA4
Reactivité: Humain
FACS
Hôte: Souris
Monoclonal
BNI3
PE
N° du produit ABIN2567241
Détail du produit anti-CTLA4 anticorps (PE)
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Antigène
Voir toutes CTLA4 Anticorps
CTLA4
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
Reactivité
Toutes les réactivités sur CTLA4 Anticorps
Humain
Hôte
Toutes les hôtes sur CTLA4 Anticorps
Souris
Clonalité
Toutes les clonalités sur CTLA4 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers CTLA4 Anticorps
Cet anticorp CTLA4 est conjugé à/à la PE
Application
Tous les applications à travers CTLA4 Anticorps.
Flow Cytometry (FACS)
Specificité
The BNI3 monoclonal antibody specifically reacts with human CD152, the Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4).
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clone
BNI3
Isotype
IgG2a kappa
Top Product
Discover our top product CTLA4 Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Stock
4 °C
Stockage commentaire
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Détails sur CTLA4
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Antigène
CTLA4
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
Autre désignation
CD152 (CTLA4 Produits )
Synonymes
anticorps CTLA-4, anticorps CTLA4, anticorps CD152, anticorps Cd152, anticorps Ctla-4, anticorps Ly-56, anticorps CD, anticorps CELIAC3, anticorps GRD4, anticorps GSE, anticorps IDDM12, anticorps sCTLA4, anticorps cytotoxic T-lymphocyte associated protein 4, anticorps cytotoxic T-lymphocyte-associated protein 4, anticorps CTLA4, anticorps Ctla4
Sujet
The BNI3 monoclonal antibody specifically reacts with human CD152, the Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4). CTLA-4 is expressed on activated CD28+ T cells, and binds the B7 family members B7-1 (CD80) and B7-2 (CD86). The structure of CTLA-4 is similar to the structure of CD28, but the two molecules seem to have opposite roles on the T lymphocytes. CTLA-4 inhibits the progression of T cell activation, while CD28 stimulates it. This result explains the stimulating role that the immobilization of BNI3 plays on the T lymphocytes proliferation induced by CD28.
ID gène
1493
UniProt
P16410
Pathways
Cancer Immune Checkpoints
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