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CTLA4 anticorps (PE)

CTLA4 Reactivité: Souris FACS Hôte: Hamster Monoclonal UC10-4F10-11 PE
N° du produit ABIN2567247
  • Antigène Voir toutes CTLA4 Anticorps
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Reactivité
    • 94
    • 64
    • 35
    • 5
    • 4
    Souris
    Hôte
    • 59
    • 50
    • 18
    • 12
    • 1
    • 1
    Hamster
    Clonalité
    • 84
    • 54
    • 2
    Monoclonal
    Conjugué
    • 63
    • 17
    • 13
    • 12
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CTLA4 est conjugé à/à la PE
    Application
    • 85
    • 64
    • 51
    • 35
    • 19
    • 14
    • 13
    • 13
    • 10
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152.
    Purification
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    Clone
    UC10-4F10-11
    Isotype
    IgG
    Top Product
    Discover our top product CTLA4 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    Stock
    4 °C
    Stockage commentaire
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • Antigène
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Autre désignation
    CD152 (CTLA4 Produits)
    Synonymes
    anticorps CTLA-4, anticorps CTLA4, anticorps CD152, anticorps Cd152, anticorps Ctla-4, anticorps Ly-56, anticorps CD, anticorps CELIAC3, anticorps GRD4, anticorps GSE, anticorps IDDM12, anticorps sCTLA4, anticorps cytotoxic T-lymphocyte associated protein 4, anticorps cytotoxic T-lymphocyte-associated protein 4, anticorps CTLA4, anticorps Ctla4
    Sujet
    The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.
    ID gène
    12477
    UniProt
    P09793
    Pathways
    Cancer Immune Checkpoints
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