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CD40 anticorps (FITC)

CD40 Reactivité: Humain FACS Hôte: Souris Monoclonal 5C3 FITC

N° du produit ABIN2567685

Fiche de données

Antigène Voir toutes CD40 Anticorps

CD40
Reactivité
189

109

21

20

6

6

4

4

4

4

2

2

2

2

2

1
Humain
Hôte
107

98

51

6

2

1

1
Souris
Anticorps secondaires appropriés
Clonalité
171

88

5
Monoclonal
Conjugué
121

24

21

19

12

8

7

4

4

4

4

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp CD40 est conjugé à/à la FITC
Application
149

96

63

53

32

26

19

19

16

14

13

13

8

6

5

5

4

4

4

3

3

3

2

2

2

2

2

1

1

1

1
Flow Cytometry (FACS)

Specificité

The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein.

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Clone

5C3

Isotype

IgG1 kappa

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anti-CD40 (CD40) (AA 21-193) antibody
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anti-CD40 (CD40) (AA 29-107) antibody
CD40 Reactivité: Humain FACS, ELISA, IHC, StM, Coat Hôte: Souris Monoclonal C40-2383 unconjugated

anti-CD40 (CD40) (C-Term) antibody
CD40 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-CD40 (CD40) (AA 71-187) antibody
CD40 Reactivité: Humain WB, IF Hôte: Souris Monoclonal 41-CD40 unconjugated

anti-CD40 (CD40) (AA 1-360) antibody
CD40 Reactivité: Humain, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-CD40 (CD40) (Extracellular Domain) antibody
CD40 Reactivité: Humain FACS, IHC, St Hôte: Souris Monoclonal 5C3 unconjugated

anti-CD40 (CD40) antibody (FITC)
CD40 Reactivité: Humain FACS Hôte: Souris Monoclonal HI40a FITC

Indications d'application

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Stock

4 °C

Stockage commentaire

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Antigène

CD40

Autre désignation

CD40 (CD40 Produits)

Synonymes

anticorps Bp50, anticorps CDW40, anticorps TNFRSF5, anticorps p50, anticorps AI326936, anticorps GP39, anticorps HIGM1, anticorps IGM, anticorps IMD3, anticorps T-BAM, anticorps TRAP, anticorps Tnfrsf5, anticorps TNFSF5, anticorps CD40 molecule, anticorps CD40 antigen, anticorps CD40, anticorps Cd40

Sujet

The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.

ID gène

958

UniProt

P25942

Pathways

Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints