CD40 anticorps
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- Antigène Voir toutes CD40 Anticorps
- CD40
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Reactivité
- Souris, Rat
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Hôte
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Hamster
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD40 est non-conjugé
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Application
- Flow Cytometry (FACS), Functional Studies (Func)
- Specificité
- The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50.
- Purification
- The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
- Clone
- HM40-3
- Isotype
- IgM kappa
- Top Product
- Discover our top product CD40 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate-buffered aqueous solution, ph7.2.
- Stock
- 4 °C
- Stockage commentaire
- The product should be stored undiluted at 4°C. Do not freeze.
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- Antigène
- CD40
- Autre désignation
- CD40 (CD40 Produits)
- Synonymes
- anticorps Bp50, anticorps CDW40, anticorps TNFRSF5, anticorps p50, anticorps AI326936, anticorps GP39, anticorps HIGM1, anticorps IGM, anticorps IMD3, anticorps T-BAM, anticorps TRAP, anticorps Tnfrsf5, anticorps TNFSF5, anticorps CD40 molecule, anticorps CD40 antigen, anticorps CD40, anticorps Cd40
- Sujet
- The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.
- ID gène
- 21939
- UniProt
- P27512
- Pathways
- Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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