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CD40 anticorps

CD40 Reactivité: Souris, Rat FACS, Func Hôte: Hamster Monoclonal HM40-3 unconjugated

N° du produit ABIN2567689

Fiche de données

Antigène Voir toutes CD40 Anticorps

CD40
Reactivité
198

114

22

20

7

6

4

4

4

4

2

2

2

2

2

1

1
Souris, Rat
Hôte
113

100

55

6

2

1

1

1
Hamster
Clonalité
183

89

5
Monoclonal
Conjugué
125

26

22

21

14

8

7

4

4

4

4

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp CD40 est non-conjugé
Application
158

97

64

54

32

32

20

19

17

14

13

13

8

6

5

5

4

4

4

3

3

3

3

2

2

2

2

2

1

1

1

1
Flow Cytometry (FACS), Functional Studies (Func)

Specificité

The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50.

Purification

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Clone

HM40-3

Isotype

IgM kappa

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CD40 Reactivité: Humain WB, IF Hôte: Souris Monoclonal 41-CD40 unconjugated

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anti-CD40 (CD40) antibody (FITC)
CD40 Reactivité: Humain FACS Hôte: Souris Monoclonal HI40a FITC

Indications d'application

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Stock

4 °C

Stockage commentaire

The product should be stored undiluted at 4°C. Do not freeze.
Antigène

CD40

Autre désignation

CD40 (CD40 Produits)

Synonymes

anticorps Bp50, anticorps CDW40, anticorps TNFRSF5, anticorps p50, anticorps AI326936, anticorps GP39, anticorps HIGM1, anticorps IGM, anticorps IMD3, anticorps T-BAM, anticorps TRAP, anticorps Tnfrsf5, anticorps TNFSF5, anticorps CD40 molecule, anticorps CD40 antigen, anticorps CD40, anticorps Cd40

Sujet

The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.

ID gène

21939

UniProt

P27512

Pathways

Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints