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IGF1R anticorps (pTyr1346)
IGF1R
Reactivité: Humain, Souris, Rat
IHC
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN2568221
Détail du produit anti-IGF1R anticorps
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Antigène
Voir toutes IGF1R Anticorps
IGF1R
(Insulin-Like Growth Factor 1 Receptor (IGF1R))
Épitope
Tous les épitopes à travers IGF1R Anticorps.
pTyr1346
Reactivité
Toutes les réactivités sur IGF1R Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur IGF1R Anticorps
Lapin
Clonalité
Toutes les clonalités sur IGF1R Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers IGF1R Anticorps
Cet anticorp IGF1R est non-conjugé
Application
Tous les applications à travers IGF1R Anticorps.
Immunohistochemistry (IHC)
Specificité
The antibody detects endogenous levels of IGF1R only when phosphorylated at tyrosine 1346.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogène
IGF1R (phospho Tyr1346) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1346 (Q-P-Y (p)-A-H) derived from Human IGF1R .
Isotype
IgG
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store antibody at -20°C for up to one year.
Détails sur IGF1R
(cache)
Antigène
IGF1R
(Insulin-Like Growth Factor 1 Receptor (IGF1R))
Autre désignation
IGF1R (IGF1R Produits )
Synonymes
anticorps CMT2N, anticorps CD221, anticorps IGFIR, anticorps IGFR, anticorps JTK13, anticorps IGFIRC, anticorps IGFR1, anticorps IGF-1R, anticorps IGF1R, anticorps DKFZp469I0618, anticorps igf-1r, anticorps xIGF-1R, anticorps xIGFR, anticorps xigf1r, anticorps A330103N21Rik, anticorps D930020L01, anticorps hyft, anticorps igf-ir, anticorps IGF-IR, anticorps IGF-IRb, anticorps wu:fb03h06, anticorps IGF-IRa, anticorps sb:eu1090, anticorps wu:fi20b10, anticorps alanyl-tRNA synthetase, anticorps insulin like growth factor 1 receptor, anticorps insulin-like growth factor 1 receptor, anticorps insulin-like growth factor 1, anticorps insulin-like growth factor I receptor, anticorps insulin like growth factor 1 receptor S homeolog, anticorps insulin-like growth factor 1b receptor, anticorps insulin-like growth factor 1a receptor, anticorps AARS, anticorps IGF1R, anticorps Igf1r, anticorps igf1r, anticorps Igf1, anticorps LOC780503, anticorps LOC100136427, anticorps igf1r.S, anticorps igf1rb, anticorps igf1ra
Sujet
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
Poids moléculaire
154 kDa
ID gène
3480
NCBI Accession
NP_000866
UniProt
P08069
Pathways
Signalisation RTK , Regulation of Hormone Metabolic Process , Regulation of Hormone Biosynthetic Process , Autophagy
Vus récemment
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