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Retinoblastoma 1 anticorps (AA 393-572)

RB1 Reactivité: Humain IP Hôte: Souris Monoclonal XZ104 unconjugated
N° du produit ABIN264372
  • Antigène Voir toutes Retinoblastoma 1 (RB1) Anticorps
    Retinoblastoma 1 (RB1)
    Épitope
    • 36
    • 29
    • 26
    • 25
    • 23
    • 21
    • 19
    • 15
    • 11
    • 10
    • 10
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 393-572
    Reactivité
    • 280
    • 119
    • 101
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 247
    • 36
    Souris
    Clonalité
    • 238
    • 45
    Monoclonal
    Conjugué
    • 134
    • 19
    • 17
    • 16
    • 11
    • 10
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Retinoblastoma 1 est non-conjugé
    Application
    • 212
    • 121
    • 110
    • 80
    • 79
    • 40
    • 33
    • 28
    • 28
    • 20
    • 16
    • 8
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    Immunoprecipitation (IP)
    Specificité
    ,Species:Human, Chicken and Mouse.
    Attributs du produit
    Synonyms: Retinoblastoma 1, Rb, p105-Rb, pRb, pp110, OSRC
    Purification
    From ascites.
    Immunogène
    Recombinant protein corresponding to amino acids 393 to 572 of the humanretinoblastoma sequence.
    Clone
    XZ104
    Isotype
    IgG1
    Top Product
    Discover our top product RB1 Anticorps primaire
  • Indications d'application
    Immunoprecipitation. This antibody is not recommended for Western blotting or Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.08 % Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    Date de péremption
    12 months
  • Antigène
    Retinoblastoma 1 (RB1)
    Autre désignation
    Retinoblastoma-Associated Protein / RB1 (RB1 Produits)
    Synonymes
    anticorps OSRC, anticorps RB, anticorps p105-Rb, anticorps pRb, anticorps pp110, anticorps Rb, anticorps Rb-1, anticorps P105-RB, anticorps PP110, anticorps RB11, anticorps zgc:154147, anticorps RB transcriptional corepressor 1, anticorps RB transcriptional corepressor like 1, anticorps retinoblastoma 1, anticorps RB1, anticorps RBL1, anticorps Rb1, anticorps rb1
    Sujet
    Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes.Synonyms: OSRC, Rb, Retinoblastoma 1, p105-Rb, pRb, pp110
    ID gène
    5925
    UniProt
    P06400
    Pathways
    Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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