CACNA1G anticorps

N° du produit ABIN265033

Détail du produit anti-CACNA1G anticorps

Antigène: CACNA1G (Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CACNA1G est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to CACNA1G.

Purification: Purified

Immunogène: Synthetic peptide derived from the rat alpha1G calcium channel conjugated to KLH.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Détails sur CACNA1G

Antigène: CACNA1G (Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))

Autre désignation: CACNA1G (CACNA1G Produits)

Synonymes: anticorps CACNA1G, anticorps cav3.1, anticorps ca(v)3.1, anticorps Ca(V)T.1, anticorps Cav3.1, anticorps NBR13, anticorps Cav3.1d, anticorps [a]1G, anticorps a1G, anticorps alpha-1G, anticorps mKIAA1123, anticorps Ca(v)3.1, anticorps calcium voltage-gated channel subunit alpha1 G, anticorps calcium channel, voltage-dependent, T type, alpha 1G subunit, anticorps calcium channel, voltage-dependent, T type, alpha 1G subunit L homeolog, anticorps CACNA1G, anticorps cacna1g, anticorps cacna1g.L, anticorps Cacna1g

Sujet: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1g gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. alpha(1G) is most likely responsible for burst firing in thalamic relay cells. These neurons burst during various thalamocortical oscillations including absence seizures the modulation of the intrinsic firing pattern mediated by alpha(1G) T-type Ca(2+) channels plays a critical role in the genesis of absence seizures in the thalamocortical pathway.Synonyms: Cav3.1, Cav3.1c, KIAA1123, NBR13, Voltage-dependent T-type calcium channel subunit alpha-1G, Voltage-gated calcium channel subunit alpha Cav3.1

ID gène: 8913

NCBI Accession: NP_061496

UniProt: O43497