GRB10 anticorps

N° du produit ABIN2650918

Détail du produit anti-GRB10 anticorps

Antigène: GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRB10 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: A synthetic peptide of human GRB10

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:1000

Commentaires:

Widely expressed in fetal and adult tissues, including fetal and postnatal liver, lung, kidney, skeletal muscle, heart, spleen, skin and brain

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur GRB10

Antigène: GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

Autre désignation: GRB10 (GRB10 Produits)

Synonymes: anticorps grb10, anticorps zgc:91987, anticorps GRB10, anticorps grb-10, anticorps grb-ir, anticorps irbp, anticorps meg1, anticorps rss, anticorps LOC100224775, anticorps 5730571D09Rik, anticorps AI325020, anticorps Meg1, anticorps mKIAA0207, anticorps RGD1566234, anticorps GRB-IR, anticorps Grb-10, anticorps IRBP, anticorps MEG1, anticorps RSS, anticorps growth factor receptor bound protein 10, anticorps growth factor receptor-bound protein 10a, anticorps growth factor receptor bound protein 10 L homeolog, anticorps growth factor receptor-bound protein 10, anticorps GRB10, anticorps grb10a, anticorps grb10, anticorps grb10.L, anticorps LOC100434903, anticorps Grb10

Sujet: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire: 67.231 kDa

ID gène: 2887

UniProt: Q13322

Pathways: Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2