Cyclin G1 anticorps

N° du produit ABIN265382

Détail du produit anti-Cyclin G1 anticorps

Antigène: Cyclin G1 (CCNG1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin G1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Cyclin G protein. (region surrounding Ile194)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Cyclin G1

Antigène: Cyclin G1 (CCNG1)

Autre désignation: Cyclin G1 (CCNG1 Produits)

Synonymes: anticorps CCNG, anticorps AI314029, anticorps CYCG, anticorps Ccng, anticorps CG 11525, anticorps CG11525, anticorps Dmel\\CG11525, anticorps anon-EST:Liang-1.25, anticorps anon-EST:Liang-2.24, anticorps clone 1.25, anticorps clone 2.24, anticorps dCycG, anticorps i205, anticorps i261, anticorps cb138, anticorps fd08g04, anticorps sb:cb138, anticorps wu:fb07e04, anticorps wu:fd08g04, anticorps zgc:56595, anticorps ccng1, anticorps cyclin G1, anticorps Cyclin G, anticorps cyclin G1 S homeolog, anticorps CCNG1, anticorps Ccng1, anticorps CycG, anticorps ccng1, anticorps ccng1.S

Sujet: Cyclins are the regulatory subunits of Cdc2 p34 and related cyclin-dependent kinases (Cdks) which play critical roles in the control of cell cycle progression. The catalytic subunit for cyclin A and B is Cdc2 p34 kinase. The Cdc2- cyclin B complex controls the G2 to M transition whereas Cdc2-cyclin A regulates S phase progression. The G1 to S transition, however, appears to be controlled by the G1 cyclins. Cyclin D1 accumulates during G1 and associates with Cdk2, Cdk4 and Cdk5. Cyclin E and Cdk2 interact during the G1 to S transition. Cyclin G contains a typical N terminal cyclin box and a carboxy terminal domain sequence homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor. Cyclin G expression is induced within 3 hours after growth stimulation and remains elevated with no apparent cell cycle dependency. Cyclin G2 shares 53 % amino acid sequence identity with cyclin G1. Peak expression of cyclin G2 is seen in late S phase, as opposed to cyclin G1 expression, which is constitutive.Synonyms: CCNG, CCNG1, CYCG1, Cyclin-G, Cyclin-G1

Poids moléculaire: approx. 29 kDa

ID gène: 900

NCBI Accession: NP_004051

UniProt: P51959

Pathways: Signalisation p53