CD137 (TNFRSF9)
(Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
Reactivité
Souris
Hôte
Hamster
Clonalité
Monoclonal
Conjugué
Cet anticorp CD137 est conjugé à/à la APC
Application
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC)
Purification
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
CDw137 is a 39 kD TNF-receptor superfamily member also known as 4-1BB, TNFRSF9, Ly-63, and ILA (Induced by Lymphocyte Activation). CDw137 is expressed as monomers, dimers, and tetramers on activated T and B cells. Interaction of CDw137 with its ligand, 4-1BBL (CDw137L), is important in T-B cell costimulation. The 17B5 antibody has been reported to block 4-1BBL costimulated T cell proliferation.