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CSF1R anticorps (Alexa Fluor 488)
CSF1R
Reactivité: Souris
FACS, ELISA (Detection)
Hôte: Rat
Monoclonal
AFS98
Alexa Fluor 488
N° du produit ABIN2657307
Détail du produit anti-CSF1R anticorps (Alexa Fluor 488)
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Antigène
Voir toutes CSF1R Anticorps
CSF1R
(Colony Stimulating Factor 1 Receptor (CSF1R))
Reactivité
Toutes les réactivités sur CSF1R Anticorps
Souris
Hôte
Toutes les hôtes sur CSF1R Anticorps
Rat
Clonalité
Toutes les clonalités sur CSF1R Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers CSF1R Anticorps
Cet anticorp CSF1R est conjugé à/à la Alexa Fluor 488
Application
Tous les applications à travers CSF1R Anticorps.
Flow Cytometry (FACS), ELISA (Detection)
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.
Clone
AFS98
Isotype
IgG2a kappa
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Discover our top product CSF1R Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Protect from prolonged exposure to light. Do not freeze.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C
Détails sur CSF1R
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Antigène
CSF1R
(Colony Stimulating Factor 1 Receptor (CSF1R))
Autre désignation
CD115 (CSF1R Produits )
Synonymes
anticorps AI323359, anticorps CD115, anticorps CSF-1R, anticorps Csfmr, anticorps Fim-2, anticorps Fms, anticorps M-CSF-R, anticorps M-CSFR, anticorps C-FMS, anticorps CSFR, anticorps FIM2, anticorps FMS, anticorps HDLS, anticorps PDGFRB, anticorps MGC89146, anticorps CSF-1-R, anticorps c-fms, anticorps mrfms, anticorps CSF1, anticorps M-CSF, anticorps csf1r, anticorps fms, anticorps panther, anticorps colony stimulating factor 1 receptor, anticorps macrophage colony-stimulating factor receptor, anticorps colony stimulating factor 1 receptor, a, anticorps Csf1r, anticorps CSF1R, anticorps m-csfr, anticorps csf1r, anticorps csf1ra
Sujet
CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.
Pathways
Signalisation RTK , Inositol Metabolic Process , Cell-Cell Junction Organization
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