TNFRSF10B anticorps (APC)

N° du produit ABIN2658556

Détail du produit anti-TNFRSF10B anticorps (APC)

Antigène: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TNFRSF10B est conjugé à/à la APC

Application: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Purification: The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Clone: DJR2-4 (7-8)

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur TNFRSF10B

Antigène: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Autre désignation: CD262 (TNFRSF10B Produits)

Synonymes: anticorps TNFRSF10B, anticorps dr5, anticorps cd262, anticorps killer, anticorps trick2, anticorps trickb, anticorps xDR-M1, anticorps xDR-M2, anticorps ztnfr9, anticorps trailr2, anticorps trick2a, anticorps trick2b, anticorps CD262, anticorps DR5, anticorps KILLER, anticorps KILLER/DR5, anticorps TRAIL-R2, anticorps TRAILR2, anticorps TRICK2, anticorps TRICK2A, anticorps TRICK2B, anticorps TRICKB, anticorps ZTNFR9, anticorps Ly98, anticorps MK, anticorps tumor necrosis factor receptor superfamily, member 10b, anticorps tumor necrosis factor receptor superfamily member 10b S homeolog, anticorps tumor necrosis factor receptor superfamily member 10b L homeolog, anticorps tumor necrosis factor receptor superfamily member 10b, anticorps TNF receptor superfamily member 10b, anticorps Tnfrsf10b, anticorps TNFRSF10B, anticorps tnfrsf10b.S, anticorps tnfrsf10b.L, anticorps tnfrsf10b

Sujet: DR5 is 55 kD member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-α, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.

Pathways: Signalisation p53, Apoptose, Positive Regulation of Endopeptidase Activity