CSF2RA anticorps (PE)

N° du produit ABIN2662955

Détail du produit anti-CSF2RA anticorps (PE)

Antigène: CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CSF2RA est conjugé à/à la PE

Application: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: 4H1

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CSF2RA

Antigène: CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))

Autre désignation: CD116 (CSF2RA Produits)

Synonymes: anticorps CD116, anticorps CDw116, anticorps CSF2R, anticorps CSF2RAX, anticorps CSF2RAY, anticorps CSF2RX, anticorps CSF2RY, anticorps GM-CSF-R-alpha, anticorps GMCSFR, anticorps GMR, anticorps SMDP4, anticorps Csfgmra, anticorps GM-CSF-Ra, anticorps GM-CSFR, anticorps colony stimulating factor 2 receptor, alpha, anticorps colony stimulating factor 2 receptor alpha subunit, anticorps colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), anticorps CSF2RA, anticorps Csf2ra

Sujet: CD116 is a 70-85 kD α chain of the GM-CSF receptor. It combines with CDw131 β chain to form the high affinity GM-CSF receptor. A soluble form of CD116, which binds GM-CSF with a relatively low affinity, has been identified. In addition, an alternatively spliced form of CD116 with an altered cytoplasmic tail has been described. CD116 is expressed on various myeloid cells including monocytes, macrophages, neutrophils, eosinophils, dendritic cells and their precursors, fibroblasts, and endothelial cells. CD116 is expressed on myeloid leukemias, osteogenic sarcoma cell lines, osteoblast-like cells and breast and lung carcinoma cell lines.

Pathways: Signalistation JAK/STAT