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CTLA4 anticorps
CTLA4
Reactivité: Souris
FACS
Hôte: Hamster
Monoclonal
UC10-4B9
unconjugated
N° du produit ABIN2664250
Détail du produit anti-CTLA4 anticorps
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Antigène
Voir toutes CTLA4 Anticorps
CTLA4
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
Reactivité
Toutes les réactivités sur CTLA4 Anticorps
Souris
Hôte
Toutes les hôtes sur CTLA4 Anticorps
Hamster
Clonalité
Toutes les clonalités sur CTLA4 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers CTLA4 Anticorps
Cet anticorp CTLA4 est non-conjugé
Application
Tous les applications à travers CTLA4 Anticorps.
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography.
Clone
UC10-4B9
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C.
Détails sur CTLA4
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Antigène
CTLA4
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
Autre désignation
CD152 (CTLA4 Produits )
Synonymes
anticorps CTLA-4, anticorps CTLA4, anticorps CD152, anticorps Cd152, anticorps Ctla-4, anticorps Ly-56, anticorps CD, anticorps CELIAC3, anticorps GRD4, anticorps GSE, anticorps IDDM12, anticorps sCTLA4, anticorps cytotoxic T-lymphocyte associated protein 4, anticorps cytotoxic T-lymphocyte-associated protein 4, anticorps CTLA4, anticorps Ctla4
Sujet
CD152, also known as CTLA-4 or Ly-56, is a 33 kD member of the immunoglobulin superfamily. It is expressed on activated T and B lymphocytes. CD152 is similar to CD28 in amino acid sequence, structure, and genomic organization and these two receptors share common B7 family counter-receptors (B7-1, B7-2). Whereas CD28 delivers a costimulatory signal in T cell activation, CTLA-4 negatively regulates cell-mediated immune responses. CD152 is thought to play a role in the induction and maintenance of immunological tolerance as well as the development of protective immunity and thymocyte regulation.
Pathways
Cancer Immune Checkpoints
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