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CD40 anticorps

CD40 Reactivité: Souris WB, IHC, IP, IF, ICFC Hôte: Rat Monoclonal 3-23 unconjugated
N° du produit ABIN2665993
  • Antigène Voir toutes CD40 Anticorps
    CD40
    Reactivité
    • 192
    • 109
    • 22
    • 20
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Souris
    Hôte
    • 107
    • 100
    • 50
    • 6
    • 2
    • 1
    • 1
    • 1
    Rat
    Clonalité
    • 172
    • 89
    • 5
    Monoclonal
    Conjugué
    • 123
    • 24
    • 21
    • 19
    • 12
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD40 est non-conjugé
    Application
    • 151
    • 96
    • 64
    • 53
    • 31
    • 27
    • 20
    • 19
    • 17
    • 14
    • 13
    • 13
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC)
    Marque
    Ultra-LEAF™
    Purification
    The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine

    Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

    Clone
    3-23
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CD40 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Agent conservateur
    Azide free
    Conseil sur la manipulation
    This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
    Stock
    4 °C
    Stockage commentaire
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Antigène
    CD40
    Autre désignation
    CD40 (CD40 Produits)
    Synonymes
    anticorps Bp50, anticorps CDW40, anticorps TNFRSF5, anticorps p50, anticorps AI326936, anticorps GP39, anticorps HIGM1, anticorps IGM, anticorps IMD3, anticorps T-BAM, anticorps TRAP, anticorps Tnfrsf5, anticorps TNFSF5, anticorps CD40 molecule, anticorps CD40 antigen, anticorps CD40, anticorps Cd40
    Sujet
    CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154(gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
    Pathways
    Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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