TRIM anticorps (AA 29-186)
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- Antigène Voir toutes TRIM (TRAT1) Anticorps
- TRIM (TRAT1) (T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1))
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Épitope
- AA 29-186
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TRIM est non-conjugé
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Application
- Intracellular Flow Cytometry (ICFC)
- Purification
- The antibody was purified by affinity chromatography.
- Clone
- TRIM-4
- Isotype
- IgG2a, IgG2a kappa
- Top Product
- Discover our top product TRAT1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Upon receipt, store undiluted between 2°C and 8°C.
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- Antigène
- TRIM (TRAT1) (T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1))
- Autre désignation
- TRIM (TRAT1 Produits)
- Synonymes
- anticorps TCRIM, anticorps TRIM, anticorps C030046M14Rik, anticorps Tcrim, anticorps Trim, anticorps T cell receptor associated transmembrane adaptor 1, anticorps T-cell receptor associated transmembrane adaptor 1, anticorps TRAT1, anticorps Trat1
- Sujet
- TRIM is a 30 kD disulfide-linked protein also known as T cell receptor interacting molecule. TRIM is a type III membrane protein containing a very short extracellular domain (8 amino acids). TRIM is highly expressed in T cells with some expression also observed in NK cells. TRIM is a signaling adaptor molecule that links extracellular and intracellular signaling. The TRIM protein is phosphorylated by Src kinases and associates with the PI3K regulatory subunit α after phosphorylation. TRIM has also been shown to associate with TCRα, β, and ζ. The TRIM-4 monoclonal antibody recognizes human TRIM and has been shown to be useful for Western blotting, intracellular staining by flow cytometry, and immunofluorescence staining.
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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