PPARGC1B anticorps (AA 850-950)

N° du produit ABIN7269253

Détail du produit anti-PPARGC1B anticorps

Antigène: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Épitope: AA 850-950

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPARGC1B est non-conjugé

Application: Western Blotting (WB)

Fonction: PGC1 beta Rabbit pAb

Séquence: SSRELKRRFE VFGEIEECEV LTRNRRGEKY GFITYRCSEH AALSLTKGAA LRKRNEPSFQ LSYGGLRHFC WPRYTDYDSN SEEALPASGK SKYEAMDFDS L

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 850-950 of human PGC1 beta (NP_001166170.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PPARGC1B

Antigène: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Autre désignation: PPARGC1B (PPARGC1B Produits)

Synonymes: anticorps PPARGC1B, anticorps 4631412G21Rik, anticorps Perc, anticorps PGC1beta, anticorps ERRL1, anticorps PERC, anticorps PGC-1(beta), anticorps PGC1B, anticorps PPARG coactivator 1 beta, anticorps peroxisome proliferative activated receptor, gamma, coactivator 1 beta, anticorps PPARGC1B, anticorps Ppargc1b

Sujet: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.,PPARGC1B,ERRL1,PERC,PGC-1(beta),PGC1B,PPARGC1B,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Endocrine and metabolic diseases,Diabetes,Cardiovascular,Lipids,Fatty Acids,PPARGC1B

Poids moléculaire: 106kDa/108kDa/110kDa/112kDa/113kDa

ID gène: 133522

UniProt: Q86YN6

Pathways: AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha