PPARGC1B anticorps

N° du produit ABIN7117364

L’anticorps Lapin Polyclonal anti-PPARGC1B a été validé pour WB et ELISA. Il convient pour détecter PPARGC1B dans des échantillons de Humain et Souris.

Aperçu rapide pour PPARGC1B anticorps (ABIN7117364)

Antigène: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPARGC1B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PPARGC1B anticorps

Fonction: PPARGC1B antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: peroxisome proliferator-activated receptor gamma, coactivator 1 beta

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PPARGC1B

Antigène: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Autre désignation: PPARGC1B

Sujet:

Synonyms: Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PGC-1-beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta)|PGC-1-related estrogen receptor alpha coactivator|PPARGC1B|PERC|PGC1|PGC1B|PPARGC1

Background: Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1(NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.

Poids moléculaire: 100-110 kDa

ID gène: 133522

UniProt: Q86YN6

Pathways: AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha