PRKACA
Reactivité: Humain, Souris, Rat, Chien
WB, IF
Hôte: Souris
Monoclonal
5B
unconjugated
Indications d'application
ELISA: 1/10000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified antibody in PBS with 0.05 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Antigène
PRKACA
(Protein Kinase A, alpha (PRKACA))
Autre désignation
PRKACA
Sujet
CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed.