IL-6 anticorps

N° du produit ABIN2689776

Il existe 4+ publications pour ce produit. L’anticorps anti-IL-6 Monoclonal Rat est utilisé pour la détection de IL-6 dans des échantillons de Humain. Il a été validé pour WB, ELISA, Neut et Inhibition.

Aperçu rapide pour IL-6 anticorps (ABIN2689776)

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-6 est non-conjugé

Application: Western Blotting (WB), ELISA, Neutralization (Neut), Blocking Antibody (Inhibition)

Clone: MQ2

Détail du produit anti-IL-6 anticorps

Attributs du produit: The MQ2-13A5 antibody reacts with human interleukin-6 (IL-6). The immunogen used to generate this hybridoma was COS-7 -expressed recombinant human IL-6. This is a neutralizing antibody. This antibody is routinely tested by ELISA. Other applications were tested during antibody development only or reported in the literature. ELISA standard curve for human IL-6.

BD Pharmingen™ Purified Rat Anti-Human IL-6 - Purified - Clone MQ2-13A5 - Isotype Rat IgG1 - Reactivity Hu - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-IL-6 (ABIN2689776)

Abrams: "Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies." dans: Current protocols in immunology / edited by John E. Coligan ... [et al.], Vol. Chapter 6, pp. Unit 6.20, (2008) (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." dans: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).

Gaines Das, Poole: "The international standard for interleukin-6. Evaluation in an international collaborative study." dans: Journal of immunological methods, Vol. 160, Issue 2, pp. 147-53, (1993) (PubMed).

Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." dans: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, (1992) (PubMed).

Détails sur IL-6

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Autre désignation: IL-6

Pathways: Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome