IL-6 anticorps (Biotin)

N° du produit ABIN2689781

Cet anticorps Rat Monoclonal détecte spécifiquement IL-6 dans WB et ELISA. Il présente une réactivité avec des échantillons de Souris. Il a été cité dans 3+ publications.

Aperçu rapide pour IL-6 anticorps (Biotin) (ABIN2689781)

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-6 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA

Clone: MP5

Détail du produit anti-IL-6 anticorps (Biotin)

Attributs du produit: The MP5-32C11 antibody reacts with mouse interleukin-6 (IL-6). The immunogen used to generate the MP5-32C11 hybridoma was recombinant mouse IL-6. This is a non-neutralizing antibody.

BD Pharmingen™ Biotin Rat Anti-Mouse IL-6 - Biotin - Clone MP5-32C11 - Isotype Rat IgG2a - Reactivity Ms - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Recombinant mouse IL-6

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Références pour anticorps anti-IL-6 (Biotin) (ABIN2689781)

Abrams: "Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies." dans: Current protocols in immunology / edited by John E. Coligan ... [et al.], Vol. Chapter 6, pp. Unit 6.20, (2008) (PubMed).

Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." dans: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, (1992) (PubMed).

Starnes, Pearce, Tewari, Yim, Zou, Abrams: "Anti-IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-alpha challenge in mice." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 145, Issue 12, pp. 4185-91, (1991) (PubMed).

Détails sur IL-6

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Autre désignation: IL-6

Pathways: Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome