Oct-2 anticorps

N° du produit ABIN271754

Détail du produit anti-Oct-2 anticorps

Antigène: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Oct-2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of OCT2/OTF2 (H3) protein. (region surrounding His3)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur Oct-2

Antigène: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Autre désignation: POU2F2 / OCT2 (POU2F2 Produits)

Synonymes: anticorps OCT2, anticorps OTF2, anticorps Oct-2, anticorps Pou2f2, anticorps Oct2a, anticorps Oct2b, anticorps Otf-2, anticorps Otf2, anticorps 2-Oct, anticorps Oct2, anticorps POU class 2 homeobox 2, anticorps POU domain, class 2, transcription factor 2, anticorps solute carrier family 22 (organic cation transporter), member 2, anticorps POU2F2, anticorps Pou2f2, anticorps SLC22A2

Sujet: Organic cation transporters (OCT) are expressed in the plasma membrane of epithelial cells from a wide range of tissues, where they function in the elimination of ndogenous amines, cationic drugs and other xenobiotics. The structure of OCTs consists of a 12-transmembrane-domain structure and a large extracellular hydrophilic loop. In humans, OCT1 is primarily expressed in the liver while OCT2 is expressed in the kidney. OCT3 is expressed in the placenta, skeletal muscle, prostate, aorta and liver. OCT3, also known as extraneuronal monoamine transporter, is widely expressed in different regions of the brain including the hippocampus, cerebellum and cerebral cortex. OCT3 mediates the uptake of several neuroactive agents, including dopamine, and may play an important role in the disposition of neurotransmitters and cationic neurotoxins in the brain. The genes encoding human OCT1-3 map to a conserved cluster at chromosome 6q26-q27.Synonyms: Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, OTF2, Oct-2, Octamer-binding protein 2, Octamer-binding transcription factor 2, Otf-2, POU domain class 2 transcription factor 2

Poids moléculaire: approx. 52 kDa

ID gène: 5452

NCBI Accession: NP_001193954

UniProt: P09086