Transglutaminase 2 anticorps

N° du produit ABIN271855

Détail du produit anti-Transglutaminase 2 anticorps

Antigène: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transglutaminase 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Transglutaminase 2 protein. (region surrounding Asp11)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur Transglutaminase 2

Antigène: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Autre désignation: Transglutaminase-2 (TGM2) (TGM2 Produits)

Synonymes: anticorps G-ALPHA-h, anticorps GNAH, anticorps TG2, anticorps TGC, anticorps tgm2, anticorps zgc:101081, anticorps TgaseII, anticorps TGM2, anticorps fc12b04, anticorps wu:fc12b04, anticorps zgc:136700, anticorps TGL2, anticorps G[a]h, anticorps TGase2, anticorps tTG, anticorps tTGas, anticorps transglutaminase 2, anticorps transglutaminase 2, C polypeptide A, anticorps transglutaminase 2b, anticorps transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), anticorps transglutaminase 2, C polypeptide, anticorps TGM2, anticorps tgm2a, anticorps Tgm2, anticorps tgm2b

Sujet: Tissue transglutaminase is a calcium activated enzyme which catalyzes the cross linking of proteins and the conjugation of polyamines to proteins. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD). CD, a genetic, immunologically mediated small bowel enteropathy that causes malabsorption, is a relatively common disorder in Western countries.Synonyms: Protein-glutamine gamma-glutamyltransferase 2, TGase C, TGase-H, Tissue transglutaminase

Poids moléculaire: approx. 77 kDa

ID gène: 7052

NCBI Accession: NP_004604

UniProt: P21980

Pathways: Tube Formation, Thromboxane A2 Receptor Signaling