Integrin beta 4 anticorps

N° du produit ABIN2742302

Détail du produit anti-Integrin beta 4 anticorps

Antigène: Integrin beta 4 (ITGB4)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 4 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Blocking Reagent (BR)

Specificité: Human ITGB4 / Integrin Beta 4

Purification: Protein G purified

Immunogène: The human squamous cell carcinoma line (UM-SCC1).

Type of Immunogen: Cells

Clone: UM-A9

Isotype: IgG2a kappa

Information d'application

Indications d'application: Approved: Block, Flo (0.5 - 1 μg/10 x10⁶), IF (0.5 - 1 μg/mL)

Usage: This antibody recognizes a protein of 205  kDa, which is identified as integrin beta 4 (ITGB4) and CD104. Its epitope is localized in the extracellular domain of integrin beta 4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. ELISA: Order BSA-free format for coating.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2°C to 8°C.

Détails sur Integrin beta 4

Antigène: Integrin beta 4 (ITGB4)

Autre désignation: ITGB4 / Integrin beta 4 (ITGB4 Produits)

Synonymes: anticorps AA407042, anticorps C230078O20, anticorps CD104, anticorps integrin subunit beta 4, anticorps integrin beta 4, anticorps ITGB4, anticorps Itgb4

Sujet: Name/Gene ID: ITGB4
Family: Integrin

Synonyms: ITGB4, CD104, Integrin beta-4, Integrin Beta 4, gp150, CD104 antigen, Integrin beta-4 subunit, Integrin, beta 4

ID gène: 3691

Pathways: Integrin Complex