ARNT anticorps (Middle Region)

N° du produit ABIN2774828

Détail du produit anti-ARNT anticorps

Antigène: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Mouton, Cobaye, Cheval, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARNT est non-conjugé

Application: Western Blotting (WB)

Séquence: QSSADKERLA RENHSEIERR RRNKMTAYIT ELSDMVPTCS ALARKPDKLT

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 93%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 93%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ARNT. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ARNT

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ARNT

Antigène: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Autre désignation: ARNT (ARNT Produits)

Synonymes: anticorps HIF-1-beta, anticorps HIF-1beta, anticorps HIF1-beta, anticorps HIF1B, anticorps HIF1BETA, anticorps TANGO, anticorps bHLHe2, anticorps D3Ertd557e, anticorps Drnt, anticorps ESTM42, anticorps Hif1b, anticorps W08714, anticorps mKIAA4051, anticorps Arnt1, anticorps ARNT, anticorps zgc:136664, anticorps arnt1, anticorps hif1b, anticorps tango, anticorps xArnt, anticorps hif1beta, anticorps hif-1beta, anticorps arnt.2, anticorps MGC68805, anticorps aryl hydrocarbon receptor nuclear translocator, anticorps aryl hydrocarbon receptor nuclear translocator S homeolog, anticorps ARNT, anticorps Arnt, anticorps arnt, anticorps arnt.S

Sujet: This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants.
Alias Symbols: HIF1B, TANGO, bHLHe2, HIF1BETA, HIF-1beta, HIF1-beta, HIF-1-beta
Protein Size: 416

Poids moléculaire: 45 kDa

ID gène: 405

NCBI Accession: NM_001197325, NP_001184254

UniProt: P27540

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, L'effet Warburg