TCF7L2 anticorps (N-Term)

N° du produit ABIN2778365

Détail du produit anti-TCF7L2 anticorps

Antigène: TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCF7L2 est non-conjugé

Application: Western Blotting (WB)

Séquence: MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN

Homologie: Cow: 100%, Dog: 75%, Guinea Pig: 75%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Tcf7l2. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TCF7L2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 459 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TCF7L2

Antigène: TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))

Autre désignation: Tcf7l2 (TCF7L2 Produits)

Synonymes: anticorps TCF4B, anticorps TCF4E, anticorps Tcf-4, anticorps Tcf4, anticorps mTcf-4B, anticorps mTcf-4E, anticorps tcf4, anticorps XTCF-4, anticorps tcf4e, anticorps TCF4, anticorps TCF-4, anticorps TCFL2, anticorps transcription factor 7 like 2, anticorps transcription factor 7-like 2, anticorps transcription factor 7 like 2, T cell specific, HMG box, anticorps transcription factor 7 like 2 L homeolog, anticorps transcription factor 7-like 2 (T-cell specific, HMG-box), anticorps TCF7L2, anticorps LOC100545943, anticorps Tcf7l2, anticorps tcf7l2, anticorps tcf7l2.L

Sujet: This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.
Alias Symbols: TCF4, TCF-4
Protein Interaction Partner: Ctnnb1, Hdac1, Hdac2, Hnf4a,
Protein Size: 619

Poids moléculaire: 68 kDa

ID gène: 6934

NCBI Accession: XM_005270084, XP_005270141

UniProt: Q9NQB0

Pathways: Signalisation WNT, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus