BAD anticorps (Middle Region)

N° du produit ABIN2779311

Cet anticorps Lapin Polyclonal détecte spécifiquement BAD dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Lapin, Boeuf (Vache), Cobaye et Cheval. Il a été cité dans 2+ publications.

Aperçu rapide pour BAD anticorps (Middle Region) (ABIN2779311)

Antigène: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAD est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BAD anticorps

Épitope: Middle Region

Fonction: BAD Antibody - middle region

Séquence: GAVEIRSRHS SYPAGTEDDE GMGEEPSPFR GRSRSAPPNL WAAQRYGREL

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against BAD. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30278-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-BAD (ABIN2779311)

Mishra, Thakur, Somal, Parmar, Yadav, Bharati, Bharti, Paul, Verma, Chouhan, Sharma, Singh, González, DOcchio, Sarkar et al.: "Expression and localization of angiopoietin family in buffalo ovarian follicles during different stages of development and modulatory role of angiopoietins on steroidogenesis and survival of cultured ..." dans: Theriogenology, Vol. 86, Issue 7, pp. 1818-33, (2016) (PubMed).

Mishra, Parmar, Yadav, Reshma, Bharati, Bharti, Paul, Chouhan, Taru Sharma, Singh, Sarkar et al.: "Expression and localization of angiopoietin family in corpus luteum during different stages of oestrous cycle and modulatory role of angiopoietins on steroidogenesis, angiogenesis and survivability ..." dans: Reproduction in domestic animals = Zuchthygiene, Vol. 51, Issue 6, pp. 855-869, (2016) (PubMed).

Détails sur BAD

Antigène: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Autre désignation: BAD

Sujet:

Background Information: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Gene Name: BCL2-associated agonist of cell death

Alternative Symbols: BBC2, BCL2L8

Protein Name: Bcl2 antagonist of cell death

Poids moléculaire: 18kDa

ID gène: 572

NCBI Accession: NP_004313

UniProt: Q92934

Pathways: Signalisation MAPK, Signalisation PI3K-Akt, Signalisation RTK, Apoptose, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events