FOXA2 anticorps (Middle Region)

N° du produit ABIN2779937

Détail du produit anti-FOXA2 anticorps

Antigène: FOXA2 (Forkhead Box A2 (FOXA2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Chien, Cobaye, Cheval, Porc, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXA2 est non-conjugé

Application: Western Blotting (WB)

Séquence: SSGGKKTAPG SQASQAQLGE AAGSASETPA GTESPHSSAS PCQEHKRGGL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Foxa2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of mouse Foxa2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 459 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FOXA2

Antigène: FOXA2 (Forkhead Box A2 (FOXA2))

Autre désignation: Foxa2 (FOXA2 Produits)

Synonymes: anticorps hnf3b, anticorps tcf3b, anticorps hnf3beta, anticorps hnf3-beta, anticorps FOXA2, anticorps HNF3B, anticorps TCF3B, anticorps HNF-3B, anticorps ax, anticorps axl, anticorps fkd1, anticorps ik:tdsubc_2g8, anticorps tdsubc_2g8, anticorps wu:fe05g04, anticorps xx:tdsubc_2g8, anticorps FoxA2-A, anticorps FoxA2a, anticorps xFD-3, anticorps xbeta-1, anticorps HNF-3b, anticorps HNF3-beta, anticorps HNF3beta, anticorps Hnf-3b, anticorps Hnf3b, anticorps Tcf-3b, anticorps Tcf3b, anticorps HNF-3BETA, anticorps forkhead box A2, anticorps forkhead box A2 L homeolog, anticorps foxa2, anticorps FOXA2, anticorps foxa2.L, anticorps Foxa2

Sujet: Foxa2 is a transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues.Foxa2 is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites.Foxa2 binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. In embryonic development Foxa2 is required for notochord formation.Foxa2 is involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs.
Alias Symbols: HNF3-beta, HNF3beta, Hnf-3b, Hnf3b, Tcf-3b, Tcf3b
Protein Interaction Partner: Ucp2, Gck, Pklr, Hnf4a, Igfbp1, Acadm, Acadvl,
Protein Size: 459

Poids moléculaire: 48 kDa

ID gène: 15376

NCBI Accession: NM_010446, NP_034576

UniProt: P35583

Pathways: Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process