NR2C1 anticorps (C-Term)
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- Antigène Voir toutes NR2C1 Anticorps
- NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR2C1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- LPALRLMNAT ITEELFFKGL IGNIRIDSVI PHILKMEPAD YNSQIIGHSI
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against NR2C1. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human NR2C1
- Top Product
- Discover our top product NR2C1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 603 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
- Autre désignation
- NR2C1 (NR2C1 Produits)
- Synonymes
- anticorps TR2, anticorps NR2C1, anticorps dor2, anticorps tr2-11, anticorps xDOR2, anticorps DKFZp468M0512, anticorps si:dkey-183c16.2, anticorps zgc:110672, anticorps 4831444H07Rik, anticorps 80.3, anticorps Eenr, anticorps Tr2-11, anticorps Tr2, anticorps Psg4, anticorps TR2-11, anticorps PSG9, anticorps nr2c1, anticorps nuclear receptor subfamily 2 group C member 1, anticorps nuclear receptor subfamily 2 group C member 1 S homeolog, anticorps nuclear receptor subfamily 2, group C, member 1, anticorps pregnancy specific beta-1-glycoprotein 4, anticorps nuclear receptor subfamily 2 group C member 1 L homeolog, anticorps NR2C1, anticorps nr2c1.S, anticorps nr2c1, anticorps Nr2c1, anticorps PSG4, anticorps nr2c1.L
- Sujet
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The nuclear orphan receptors NR2C1 represses transcription and binds DNA as a homodimer. NR2C1 binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. NR2C1 may function as a negative modulator to suppress androgen receptor function in prostate cancer. NR2C1 may exert an important repressor in regulating ER activity in mammary glands. The nuclear orphan receptors TR2 (NR2C1) and TR4 form a heterodimer that binds to the epsilon and gamma globin promoter DR1 sites
Alias Symbols: TR2, TR2-11
Protein Interaction Partner: PSPC1, MBD3, SIN3A, RCOR1, KDM1A, POLD3, TRIM28, RBM39, MTA2, MTA1, HDAC3, NR2C2, SMARCA4, SFPQ, RBBP7, RBBP4, NONO, HDAC2, HDAC1, HCFC1, DNMT1, CHD4, NUDT3, UBC, PML, HDAC4, NRIP1, AR, ESR1,
Protein Size: 603 - Poids moléculaire
- 67 kDa
- ID gène
- 7181
- NCBI Accession
- NM_003297, NP_003288
- UniProt
- Q15625
- Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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