NFATC1 anticorps (N-Term)
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- Antigène Voir toutes NFATC1 Anticorps
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NFATC1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- PSTSFPVPSK FPLGPAAAVF GRGETLGPAP RAGGTMKSAE EEHYGYASSN
- Homologie
- Guinea Pig: 86%, Human: 100%, Mouse: 79%, Rat: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against NFATC1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human NFATC1
- Top Product
- Discover our top product NFATC1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 716 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
- Autre désignation
- NFATC1 (NFATC1 Produits)
- Synonymes
- anticorps nf-atc, anticorps nfat2, anticorps nfatc, anticorps si:ch211-198c22.2, anticorps NFATC1, anticorps 2210017P03Rik, anticorps AI449492, anticorps AV076380, anticorps NF-ATc, anticorps NFAT2, anticorps NFATc, anticorps Nfatcb, anticorps NF-ATC, anticorps NF-ATc1, anticorps NFAT, anticorps NFATmac, anticorps nuclear factor of activated T-cells 1, anticorps nuclear factor of activated T-cells 1 L homeolog, anticorps nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1, anticorps nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1, anticorps NFATC1, anticorps nfatc1.L, anticorps nfatc1, anticorps Nfatc1
- Sujet
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NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of this protein may regulate inducible expression of different cytokine genes. The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Alias Symbols: MGC138448, NF-ATC, NFAT2, NFATc
Protein Interaction Partner: YWHAQ, OGT, PML, GZF1, FOXP3, HDAC4, PIAS1, SUMO1, UBE2I, RPS6KB1, RPS6KA3, HDAC2, HDAC1, HNRNPA1, TUBA1A, KPNB1, HDAC5, KAT2B, EP300, PARP1, HDAC3, PPP3R1, MAPK14, GNB2L1, PRKCA, SPI1, PIM1, EGR2, EGR1,
Protein Size: 716 - Poids moléculaire
- 78 kDa
- ID gène
- 4772
- NCBI Accession
- NM_172390, NP_765978
- UniProt
- Q2M1S3
- Pathways
- Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway
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