SLC8A1 anticorps (N-Term)

N° du produit ABIN2781671

Détail du produit anti-SLC8A1 anticorps

Antigène: SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC8A1 est non-conjugé

Application: Western Blotting (WB)

Séquence: CTGSYYCKKG VILPIWEPQD PSFGDKIARA TVYFVAMVYM FLGVSIIADR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%

Attributs du produit: This is a rabbit polyclonal antibody against SLC8A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of human SLC8A1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SLC8A1

Antigène: SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))

Autre désignation: SLC8A1 (SLC8A1 Produits)

Synonymes: anticorps NCX1, anticorps AI852629, anticorps AV344025, anticorps D930008O12Rik, anticorps Ncx1, anticorps Ncx, anticorps SLC8A1, anticorps ncx1n, anticorps solute carrier family 8 member A1, anticorps solute carrier family 8 (sodium/calcium exchanger), member 1, anticorps solute carrier family 8 (sodium/calcium exchanger), member 1b, anticorps sodium/calcium exchanger 1, anticorps SLC8A1, anticorps Slc8a1, anticorps slc8a1b, anticorps Tsp_07038

Sujet: In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM, Apr 2004]
Alias Symbols: NCX1
Protein Size: 664

Poids moléculaire: 73 kDa

ID gène: 6546

NCBI Accession: NM_001112800, NP_001106271

UniProt: P32418

Pathways: Myometrial Relaxation and Contraction