ACVRL1 anticorps (N-Term)

N° du produit ABIN2781759

Détail du produit anti-ACVRL1 anticorps

Antigène: ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Porc, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACVRL1 est non-conjugé

Application: Western Blotting (WB)

Séquence: SPHCKGPTCR GAWCTVVLVR EEGRHPQEHR GCGNLHRELC RGRPTEFVNH

Homologie: Dog: 100%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against ACVRL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ACVRL1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 503 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ACVRL1

Antigène: ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))

Autre désignation: ACVRL1 (ACVRL1 Produits)

Synonymes: anticorps ACVRL1, anticorps vgb, anticorps alk1, anticorps zehn1109, anticorps hm:zehn1109, anticorps ACVRLK1, anticorps ALK-1, anticorps ALK1, anticorps HHT, anticorps HHT2, anticorps ORW2, anticorps SKR3, anticorps TSR-I, anticorps R-3, anticorps R3, anticorps SETHKIR, anticorps AI115505, anticorps AI427544, anticorps Acvrlk1, anticorps Alk1, anticorps activin A receptor like type 1, anticorps activin A receptor type II-like 1, anticorps activin A receptor, type II-like 1, anticorps ACVRL1, anticorps acvrl1, anticorps Acvrl1

Sujet: ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Alias Symbols: ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
Protein Interaction Partner: TGFBR1, TGFB1, INHBA, SMAD1, PEG10, NR1H2, FKBP1A, CSNK2B, ENG, BAMBI, HSP90AA1, IGSF1, TSC22D1, SNX6, TGFBRAP1, XIAP, TGFB3, TGFBR2, ACVR2A,
Protein Size: 503

Poids moléculaire: 55 kDa

ID gène: 94

NCBI Accession: NM_000020, NP_000011

UniProt: P37023