PTPRE anticorps (Middle Region)

N° du produit ABIN2782718

Détail du produit anti-PTPRE anticorps

Antigène: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cheval, Cobaye, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPRE est non-conjugé

Application: Western Blotting (WB)

Séquence: VILSMKRGQE YTDYINASFI DGYRQKDYFI ATQGPLAHTV EDFWRMIWEW

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PTPRE. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PTPRE

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 700 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PTPRE

Antigène: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Autre désignation: PTPRE (PTPRE Produits)

Synonymes: anticorps ptpra, anticorps HPTPE, anticorps PTPE, anticorps R-PTP-EPSILON, anticorps PTPe, anticorps PTPepsilon, anticorps RPTPepsilon, anticorps protein tyrosine phosphatase, receptor type E L homeolog, anticorps protein tyrosine phosphatase, receptor type E, anticorps protein tyrosine phosphatase, receptor type, E, anticorps ptpre.L, anticorps PTPRE, anticorps Ptpre

Sujet: PTPRE is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.
Alias Symbols: DKFZp313F1310, HPTPE, PTPE, R-PTP-EPSILON
Protein Interaction Partner: UBC, MAPK3, MAPK1, KCNB1, KCNA5, PTPRD, PTPRS, PTPRE, SRC, YES1, FYN, GRB2,
Protein Size: 700

Poids moléculaire: 81 kDa

ID gène: 5791

NCBI Accession: NM_006504, NP_006495

UniProt: P23469