PVRL2 anticorps (Middle Region)

N° du produit ABIN2783151

Détail du produit anti-PVRL2 anticorps

Antigène: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Épitope: Middle Region

Reactivité: Humain, Souris, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PVRL2 est non-conjugé

Application: Western Blotting (WB)

Séquence: MEPDGKDEEE EEEEEKAEKG LMLPPPPALE DDMESQLDGS LISRRAVYV

Homologie: Human: 100%, Mouse: 93%, Pig: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PVRL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PVRL2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 479 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PVRL2

Antigène: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Autre désignation: PVRL2 (PVRL2 Produits)

Synonymes: anticorps prr2, anticorps AI325026, anticorps AI987993, anticorps Cd112, anticorps MPH, anticorps Pvr, anticorps Pvs, anticorps nectin-2, anticorps CD112, anticorps HVEB, anticorps PRR2, anticorps PVRR2, anticorps nectin cell adhesion molecule 2, anticorps Nectin2, anticorps NECTIN2

Sujet: This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: CD112, HVEB, PRR2, PVRR2
Protein Interaction Partner: KRTAP10-3, KRTAP10-5, KRTAP10-1, KRTAP10-7, NOTCH2NL, SIAH1, MDFI, KRTAP5-9, TIGIT, PVRL4, TNFRSF12A, PVRL3, PVRL2, LYRM4, DUS2, USP53, UBC, MAPK6, ATP5J2, PICK1, CD226, MLLT4,
Protein Size: 479

Poids moléculaire: 48 kDa

ID gène: 5819

NCBI Accession: NM_002856, NP_002847

UniProt: Q0MSE5

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization