POLD2 anticorps (N-Term)

N° du produit ABIN2783466

Détail du produit anti-POLD2 anticorps

Antigène: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Lapin, Boeuf (Vache), Cobaye, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLD2 est non-conjugé

Application: Western Blotting (WB)

Séquence: LREVSEEHNL LPQPPRSKYI HPDDELVLED ELQRIKLKGT IDVSKLVTGT

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against POLD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human POLD2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 469 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur POLD2

Antigène: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Autre désignation: POLD2 (POLD2 Produits)

Synonymes: anticorps 50kDa, anticorps p50, anticorps po1D2, anticorps cdc1, anticorps si:dz150f13.3, anticorps zgc:55633, anticorps zgc:77043, anticorps DNA polymerase delta 2, accessory subunit, anticorps polymerase (DNA directed), delta 2, regulatory subunit, anticorps polymerase (DNA directed), delta 2, accessory subunit L homeolog, anticorps POLD2, anticorps Pold2, anticorps pold2.L, anticorps pold2

Sujet: This protein is a DNA polymerase delta complex ,it involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen, the multisubunit replication factor C, and the 4 subunit polymerase complex: POLD1, POLD2, POLD3, and POLD4The DNA polymerase delta complex is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen (PCNA, MIM 176740), the multisubunit replication factor C (see MIM 102579), and the 4 subunit polymerase complex: POLD1 (MIM 174761), POLD2, POLD3 (MIM 611415), and POLD4 (MIM 611525) (Liu and Warbrick, 2006 [PubMed 16934752]).[supplied by OMIM].
Alias Symbols: -
Protein Interaction Partner: UBC, SPRTN, FOXK1, FAM129A, XRN1, POLD1, MMS19, POLD4, CCHCR1, SOX12, EP300, UBD, BBLF2-BBLF3, POLD3, PCNA, POLDIP3, POLDIP2, KCTD13, WRNIP1, LSM6, WRN, CDK2, CDKN1A,
Protein Size: 469

Poids moléculaire: 51 kDa

ID gène: 5425

NCBI Accession: NM_006230, NP_006221

UniProt: P49005

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA