TRKB anticorps (C-Term)

N° du produit ABIN2784510

Détail du produit anti-TRKB anticorps

Antigène: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Épitope: C-Term

Reactivité: Humain, Rat, Lapin, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRKB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: DFSWFGFGKV KSRQGVGPAS VISNDDDSAS PLHHISNGSN TPSSSEGGPD

Homologie: Cow: 88%, Horse: 100%, Human: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NTRK2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human NTRK2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 553 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRKB

Antigène: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Autre désignation: NTRK2 (NTRK2 Produits)

Synonymes: anticorps trkb, anticorps trkb-b, anticorps xtrkb, anticorps si:ch211-220b11.1, anticorps trkB2, anticorps NTRK2, anticorps ntrk2, anticorps gp145-trkb, anticorps TRKB, anticorps GP145-TrkB, anticorps trk-B, anticorps AI848316, anticorps C030027L06Rik, anticorps Tkrb, anticorps trkB, anticorps RATTRKB1, anticorps TRKB1, anticorps Trk-B, anticorps TrkB, anticorps neurotrophic receptor tyrosine kinase 2, anticorps neurotrophic receptor tyrosine kinase 2 L homeolog, anticorps neurotrophic tyrosine kinase, receptor, type 2b, anticorps neurotrophic receptor tyrosine kinase 2 S homeolog, anticorps neurotrophic tyrosine kinase, receptor, type 2, anticorps NTRK2, anticorps ntrk2.L, anticorps ntrk2b, anticorps ntrk2.S, anticorps ntrk2, anticorps Ntrk2

Sujet: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders.
Alias Symbols: GP145-TrkB, TRKB, trk-B
Protein Interaction Partner: TNK2, RANBP9, POLR2G, HSP90AA1, AP1B1, NMNAT1, UBC, NTF4, Nedd4, SHC2, KIDINS220, DOK5, SH2B2, SH2B1, SHC3, RASGRF1, UBB, FRS3, GIPC1, NCK2, DYNLL1, SQSTM1, SHC1, NCK1, NTRK2, PTPN1, PTPN11, PLCG1, NTF3, NGFR, FYN, BDNF, TRAF6, PIK3R1, FRS2,
Protein Size: 553

Poids moléculaire: 57 kDa

ID gène: 4915

NCBI Accession: NM_001018065, NP_001018075

UniProt: Q8WXJ5

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Skeletal Muscle Fiber Development, Feeding Behaviour, Dicarboxylic Acid Transport