TdT anticorps (Middle Region)
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- Antigène Voir toutes TdT (DNTT) Anticorps
- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Cheval, Chien, Boeuf (Vache), Cobaye, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TdT est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LRRYATHERK MILDNHALYD KTKRIFLKAE SEEEIFAHLG LDYIEPWERN
- Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 91%, Rabbit: 93%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against DNTT. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human DNTT
- Top Product
- Discover our top product DNTT Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 509 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
- Autre désignation
- DNTT (DNTT Produits)
- Synonymes
- anticorps TdT, anticorps TDT, anticorps BB160593, anticorps Tdt, anticorps dntt-A, anticorps dntt, anticorps DNA nucleotidylexotransferase, anticorps deoxynucleotidyltransferase, terminal, anticorps DNA nucleotidylexotransferase L homeolog, anticorps terminal deoxynucleotidyl transferase, anticorps DNTT, anticorps dntt, anticorps Dntt, anticorps dntt.L, anticorps tdt
- Sujet
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DNTT is the template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Alias Symbols: TDT
Protein Interaction Partner: REL, APOA1, DNTTIP1, UBC, PRPF19, DNTTIP2, PCNA, XRCC6, ABTB2, CUL3,
Protein Size: 509 - Poids moléculaire
- 58 kDa
- ID gène
- 1791
- NCBI Accession
- NM_004088, NP_004079
- UniProt
- P04053
- Pathways
- Réparation de l'ADN
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