ARFGAP1 anticorps (Middle Region)

N° du produit ABIN2787084

Cet anticorps anti-ARFGAP1 est un anticorps Lapin Polyclonal détectant ARFGAP1 dans WB. Adapté pour Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache) et Cobaye.

Aperçu rapide pour ARFGAP1 anticorps (Middle Region) (ABIN2787084)

Antigène: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARFGAP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ARFGAP1 anticorps

Épitope: Middle Region

Séquence: GQPQSVTASS DKAFEDWLND DLGSYQGAQG NRYVGFGNTP PPQKKEDDFL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ARFGAP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ARFGAP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 406 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ARFGAP1

Antigène: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Autre désignation: ARFGAP1

Sujet: The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ARF1GAP, HRIHFB2281, MGC39924
Protein Interaction Partner: KRTAP10-9, KRTAP9-2, KRTAP3-2, GABARAPL2, GRN, FOS, TRIM23, UBC, RPL22, HK1, RAD52, RPL11, RFC3, PRKACB, APOE, APOC3, APOB, ASB10, RASIP1, RAB23, COPS5, MED27, REEP5, APP, LRRK2, MAP1LC3B, TK1, SMN1, TMED2, CYTH2, COPA, CSNK1D, RGS2, KDELR1, ARF1,
Protein Size: 406

Poids moléculaire: 45 kDa

ID gène: 55738

NCBI Accession: NM_018209, NP_060679

UniProt: Q8N6T3

Pathways: Signalisation p53, ER-Nucleus Signaling, Unfolded Protein Response