RAP1 anticorps (Middle Region)

N° du produit ABIN2787163

Détail du produit anti-RAP1 anticorps

Antigène: RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: LTYVKENARS PSSVTGNALW KAMEKSSLTQ HSWQSLKDRY LKHLRGQEHK

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Terf2ip. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 286 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RAP1

Antigène: RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))

Autre désignation: Terf2ip (TERF2IP Produits)

Synonymes: anticorps DRIP5, anticorps RAP1, anticorps Rap1, anticorps cRAP1, anticorps TERF2 interacting protein, anticorps telomeric repeat binding factor 2, interacting protein, anticorps TERF2IP, anticorps Terf2ip

Sujet: Terf2ip acts both as a regulator of telomere function and as a transcription regulator. It is involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length.
Alias Symbols: Rap1
Protein Size: 286

Poids moléculaire: 31 kDa

ID gène: 57321

NCBI Accession: NM_020584, NP_065609

UniProt: Q91VL8

Pathways: Cycle Cellulaire, Telomere Maintenance