Stanniocalcin 2 anticorps (C-Term)

N° du produit ABIN2789750

Détail du produit anti-Stanniocalcin 2 anticorps

Antigène: Stanniocalcin 2 (STC2)

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Stanniocalcin 2 est non-conjugé

Application: Western Blotting (WB)

Séquence: HHLPEPSSRE TGRGAKGERG SKSHPNAHAR GRVGGLGAQG PSGSSEWEDE

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against STC2. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 302 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Stanniocalcin 2

Antigène: Stanniocalcin 2 (STC2)

Autre désignation: STC2 (STC2 Produits)

Synonymes: anticorps STC2, anticorps im:6908722, anticorps stc2, anticorps wu:fd13c01, anticorps zgc:136650, anticorps MGC145691, anticorps STC-2, anticorps STCRP, anticorps AW125853, anticorps Stc2l, anticorps mustc2, anticorps stanniocalcin 2, anticorps stanniocalcin 2a, anticorps STC2, anticorps stc2a, anticorps stc2, anticorps Stc2

Sujet: This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
Alias Symbols: STC-2, STCRP
Protein Interaction Partner: UBC, ELAVL1, POLR2C, POLR3F, ARHGEF40, EIF2B3, CARHSP1, PEBP1, PPP1R8, AIFM1, PTN, ADAM11, ARRB2,
Protein Size: 302

Poids moléculaire: 31 kDa

ID gène: 8614

NCBI Accession: NM_003714, NP_003705

UniProt: O76061

Pathways: Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome