FAM33A anticorps (N-Term)

N° du produit ABIN2797862

Détail du produit anti-FAM33A anticorps

Antigène: FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))

Épitope: AA 9-37, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM33A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: Rabbit Anti-Human SKA2 (N-term) Antibody

Immunogène: This SKA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-37 amino acids from the N-terminal region of human SKA2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50SKA2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur FAM33A

Antigène: FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))

Autre désignation: SKA2 (FAM33A Produits)

Synonymes: anticorps FAM33A, anticorps 1110001A07Rik, anticorps C78640, anticorps Fam33a, anticorps RGD1307084, anticorps fam33a, anticorps spindle and kinetochore associated complex subunit 2, anticorps Spindle and kinetochore-associated protein 2, anticorps SKA2, anticorps Ska2, anticorps ska2

Sujet:

Target Description: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it is required for SKA1 localization.

Gene Symbol: SKA2

Poids moléculaire: 14188 Da

ID gène: 348235

UniProt: Q8WVK7

Pathways: M Phase