CBX4 anticorps (AA 401-500) (Alexa Fluor 594)
-
- Antigène Voir toutes CBX4 Anticorps
- CBX4 (Chromobox Homolog 4 (CBX4))
-
Épitope
- AA 401-500
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp CBX4 est conjugé à/à la Alexa Fluor 594
-
Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Dog,Sheep,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human CBX4
- Isotype
- IgG
- Top Product
- Discover our top product CBX4 Anticorps primaire
-
anti-Chromobox Homolog 4 (CBX4) (AA 397-514) antibody
CBX4 Reactivité: Humain WB, ELISA, IHC, ICC, FACS Hôte: Souris Monoclonal 6C5G3 unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 1-160) antibodyCBX4 Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 80-110), (N-Term) antibodyCBX4 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB2931 unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 401-560) antibodyCBX4 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 401-500) antibodyCBX4 Reactivité: Humain, Souris WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 410-437), (C-Term) antibodyCBX4 Reactivité: Humain WB Hôte: Lapin Polyclonal RB2934 unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 1-290) antibodyCBX4 Reactivité: Humain WB Hôte: Souris Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 401-560) antibodyCBX4 Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (N-Term) antibodyCBX4 Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 150-200) antibodyCBX4 Reactivité: Humain, Souris, Chien, Lapin, Boeuf (Vache), Cobaye, Porc IHC, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
-
- Indications d'application
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- CBX4 (Chromobox Homolog 4 (CBX4))
- Autre désignation
- CBX4 (CBX4 Produits)
- Synonymes
- anticorps MPc2, anticorps PC2, anticorps NBP16, anticorps XPolycomb, anticorps cbx4-a, anticorps im:6911625, anticorps zgc:158588, anticorps chromobox 4, anticorps chromobox 4 S homeolog, anticorps chromobox homolog 4, anticorps chromobox homolog 4 (Pc class homolog, Drosophila), anticorps CBX4, anticorps Cbx4, anticorps cbx4.S, anticorps cbx4
- Sujet
-
Synonyms: PC2, NBP16, E3 SUMO-protein ligase CBX4, Chromobox protein homolog 4, Polycomb 2 homolog, hPc2, CBX4
Background: E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
- ID gène
- 8535
- UniProt
- O00257
-
