BAG5 anticorps (AA 101-200) (Alexa Fluor 594)

N° du produit ABIN2810161

Détail du produit anti-BAG5 anticorps (Alexa Fluor 594)

Antigène: BAG5 (BCL2-Associated Athanogene 5 (BAG5))

Épitope: AA 101-200

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAG5 est conjugé à/à la Alexa Fluor 594

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BAG5

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur BAG5

Antigène: BAG5 (BCL2-Associated Athanogene 5 (BAG5))

Autre désignation: BAG5 (BAG5 Produits)

Synonymes: anticorps BAG-5, anticorps bag-5, anticorps 1600025G07Rik, anticorps 4930405J06Rik, anticorps zgc:114117, anticorps BAG5, anticorps ATBAG5, anticorps BCL-2-associated athanogene 5, anticorps F12F1.7, anticorps F12F1_7, anticorps BCL2 associated athanogene 5, anticorps BCL2-associated athanogene 5, anticorps BCL-2-associated athanogene 5, anticorps BAG5, anticorps bag5, anticorps Bag5

Sujet:

Synonyms: BAG family molecular chaperone regulator 5, BAG 5, BAG-5, BCL2 associated athanogene 5, KIAA0873, BAG5_HUMAN.

Background: BAG5 is a member of the BAG1 related protein family. BAG1 is an anti apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL 2, Raf protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. A BAG domain near the C terminus, may bind and inhibit the chaperone activity of Hsc70/Hsp70. It has been hypothesized that the BAG5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70?s anti apoptotic function. It is believed that BAG5 will play an important role in the mechanisms of neuronal death. BAG5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAGheterodimerization.

ID gène: 9529

Pathways: SARS-CoV-2 Protein Interactome